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Exploring Gene-Based Diets with UVA Health Researchers


A team of researchers at UVA Health is delving into nutrigenomics for precision health, believing that one’s own genes could be the key to better health. The team, including Sibylle Kranz, Susanna Keller, Heather Ferris, and Mete Civelek, aims to study how different diets impact body weight, nutrient metabolism, and gene expression. Their preclinical study involved feeding genetically diverse mouse strains American, Mediterranean, vegetarian, and vegan diets, revealing that nutrient transporters in adipose tissue vary with sugar intake in certain strains.

The team envisions a future where individuals can undergo genetic and nutrient testing to create personalized diets that address health issues like maintaining a healthy weight and reducing the risk of diseases such as cancer, diabetes, and dementia. This innovative approach could revolutionize healthcare by providing evidence-based dietary recommendations tailored to individual genetic backgrounds.

This groundbreaking research was featured in the October 2024 issue of a publication, showcasing the potential of nutrigenomics in shaping the future of healthcare. As the team continues to unravel the intricate relationship between genes and nutrition, the possibilities for personalized and effective health interventions are endless.

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